12 month outcomes of Prostatic Urethral Lift (PUL) in retention patients: Real-World and PULSAR
BAUS ePoster online library. Rochester M. 06/21/21; 319068; p3-1
Disclosure(s): Honorariums from Teleflex for training And lecturing
Mr. Mark Rochester
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Abstract
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INTRODUCTION:
Performance of MISTs for BPH subjects in acute urinary retention status should be assessed in both controlled and real-world settings. We report and compare outcomes of the minimally invasive PUL procedure in retention patients from real-world and controlled PULSAR studies.
METHODS:
The controlled PULSAR study assessed outcomes of 52 retention subjects with ≥ 1 failed TWOC on alpha blocker. The international Real-World Retrospective (RWR) database included 512 subjects in urinary retention at baseline. Baseline demographics, symptom outcomes, and AE and catheterization rates were compared between RWR retention (RWR-r) and PULSAR subjects.
RESULTS:
Baseline demographics of age and prostate size were similar between RWR-r and PULSAR subjects. PULSAR subjects were catheterized on average for 132 days prior to PUL; 60% of RWR-r subjects were catheterized for <30 days prior. SHIM erectile function was preserved. 90% of PULSAR subjects felt better and 88% would recommend PUL. Of the 12 PULSAR patients with UDS data, pdet@Qmax and BOOI improved from baseline, and 5 changed from obstructed to unobstructed or equivocal. Of those that remained obstructed, 86% were catheter-independent and 83% felt 'very much better.' PULSAR IPSS, Qmax, and PVR outcomes were equivalent to RWR-r; PULSAR QoL was significantly better. Catheter-independence rates were better for RWR subjects. Overall AE rate was not elevated in RWR-r subjects vs. PULSAR.
CONCLUSIONS:
The large multicenter RWR and the controlled PULSAR study reveal stable outcomes at 12 months, indicating that PUL is effective in retention patients and may be a viable option for these BPH patients.
Performance of MISTs for BPH subjects in acute urinary retention status should be assessed in both controlled and real-world settings. We report and compare outcomes of the minimally invasive PUL procedure in retention patients from real-world and controlled PULSAR studies.
METHODS:
The controlled PULSAR study assessed outcomes of 52 retention subjects with ≥ 1 failed TWOC on alpha blocker. The international Real-World Retrospective (RWR) database included 512 subjects in urinary retention at baseline. Baseline demographics, symptom outcomes, and AE and catheterization rates were compared between RWR retention (RWR-r) and PULSAR subjects.
RESULTS:
Baseline demographics of age and prostate size were similar between RWR-r and PULSAR subjects. PULSAR subjects were catheterized on average for 132 days prior to PUL; 60% of RWR-r subjects were catheterized for <30 days prior. SHIM erectile function was preserved. 90% of PULSAR subjects felt better and 88% would recommend PUL. Of the 12 PULSAR patients with UDS data, pdet@Qmax and BOOI improved from baseline, and 5 changed from obstructed to unobstructed or equivocal. Of those that remained obstructed, 86% were catheter-independent and 83% felt 'very much better.' PULSAR IPSS, Qmax, and PVR outcomes were equivalent to RWR-r; PULSAR QoL was significantly better. Catheter-independence rates were better for RWR subjects. Overall AE rate was not elevated in RWR-r subjects vs. PULSAR.
CONCLUSIONS:
The large multicenter RWR and the controlled PULSAR study reveal stable outcomes at 12 months, indicating that PUL is effective in retention patients and may be a viable option for these BPH patients.
INTRODUCTION:
Performance of MISTs for BPH subjects in acute urinary retention status should be assessed in both controlled and real-world settings. We report and compare outcomes of the minimally invasive PUL procedure in retention patients from real-world and controlled PULSAR studies.
METHODS:
The controlled PULSAR study assessed outcomes of 52 retention subjects with ≥ 1 failed TWOC on alpha blocker. The international Real-World Retrospective (RWR) database included 512 subjects in urinary retention at baseline. Baseline demographics, symptom outcomes, and AE and catheterization rates were compared between RWR retention (RWR-r) and PULSAR subjects.
RESULTS:
Baseline demographics of age and prostate size were similar between RWR-r and PULSAR subjects. PULSAR subjects were catheterized on average for 132 days prior to PUL; 60% of RWR-r subjects were catheterized for <30 days prior. SHIM erectile function was preserved. 90% of PULSAR subjects felt better and 88% would recommend PUL. Of the 12 PULSAR patients with UDS data, pdet@Qmax and BOOI improved from baseline, and 5 changed from obstructed to unobstructed or equivocal. Of those that remained obstructed, 86% were catheter-independent and 83% felt 'very much better.' PULSAR IPSS, Qmax, and PVR outcomes were equivalent to RWR-r; PULSAR QoL was significantly better. Catheter-independence rates were better for RWR subjects. Overall AE rate was not elevated in RWR-r subjects vs. PULSAR.
CONCLUSIONS:
The large multicenter RWR and the controlled PULSAR study reveal stable outcomes at 12 months, indicating that PUL is effective in retention patients and may be a viable option for these BPH patients.
Performance of MISTs for BPH subjects in acute urinary retention status should be assessed in both controlled and real-world settings. We report and compare outcomes of the minimally invasive PUL procedure in retention patients from real-world and controlled PULSAR studies.
METHODS:
The controlled PULSAR study assessed outcomes of 52 retention subjects with ≥ 1 failed TWOC on alpha blocker. The international Real-World Retrospective (RWR) database included 512 subjects in urinary retention at baseline. Baseline demographics, symptom outcomes, and AE and catheterization rates were compared between RWR retention (RWR-r) and PULSAR subjects.
RESULTS:
Baseline demographics of age and prostate size were similar between RWR-r and PULSAR subjects. PULSAR subjects were catheterized on average for 132 days prior to PUL; 60% of RWR-r subjects were catheterized for <30 days prior. SHIM erectile function was preserved. 90% of PULSAR subjects felt better and 88% would recommend PUL. Of the 12 PULSAR patients with UDS data, pdet@Qmax and BOOI improved from baseline, and 5 changed from obstructed to unobstructed or equivocal. Of those that remained obstructed, 86% were catheter-independent and 83% felt 'very much better.' PULSAR IPSS, Qmax, and PVR outcomes were equivalent to RWR-r; PULSAR QoL was significantly better. Catheter-independence rates were better for RWR subjects. Overall AE rate was not elevated in RWR-r subjects vs. PULSAR.
CONCLUSIONS:
The large multicenter RWR and the controlled PULSAR study reveal stable outcomes at 12 months, indicating that PUL is effective in retention patients and may be a viable option for these BPH patients.
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